diff --git a/CHANGELOG.md b/CHANGELOG.md
index 837a9fd9..cb58c0c9 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,6 +10,7 @@ Package updates:
 
 Control panel:
 
+* Allow setting the backup location's S3 region name for non-AWS S3-compatible backup hosts.
 * Control panel pages can be opened in a new tab/window and bookmarked and browser history navigation now works.
 * Add a Copy button to put the rsync backup public key on clipboard.
 * Allow secondary DNS xfr: items added in the control panel to be hostnames too.
diff --git a/management/backup.py b/management/backup.py
index 99c3d60e..06285ba5 100755
--- a/management/backup.py
+++ b/management/backup.py
@@ -202,7 +202,9 @@ def get_duplicity_target_url(config):
 		# the target URL must be the bucket name. The hostname is passed
 		# via get_duplicity_additional_args. Move the first part of the
 		# path (the bucket name) into the hostname URL component, and leave
-		# the rest for the path.
+		# the rest for the path. (The S3 region name is also stored in the
+		# hostname part of the URL, in the username portion, which we also
+		# have to drop here).
 		target[1], target[2] = target[2].lstrip('/').split('/', 1)
 
 		target = urlunsplit(target)
@@ -230,10 +232,15 @@ def get_duplicity_additional_args(env):
 		]
 	elif get_target_type(config) == 's3':
 		# See note about hostname in get_duplicity_target_url.
+		# The region name, which is required by some non-AWS endpoints,
+		# is saved inside the username portion of the URL.
 		from urllib.parse import urlsplit, urlunsplit
 		target = urlsplit(config["target"])
-		endpoint_url = urlunsplit(("https", target.netloc, '', '', ''))
-		return ["--s3-endpoint-url",  endpoint_url]
+		endpoint_url = urlunsplit(("https", target.hostname, '', '', ''))
+		args = ["--s3-endpoint-url", endpoint_url]
+		if target.username: # region name is stuffed here
+			args += ["--s3-region-name", target.username]
+		return args
 
 	return []
 
diff --git a/management/templates/system-backup.html b/management/templates/system-backup.html
index 422b2a0e..f7305518 100644
--- a/management/templates/system-backup.html
+++ b/management/templates/system-backup.html
@@ -5,7 +5,7 @@
 
 <h2>Backup Status</h2>
 
-<p>The box makes an incremental backup each night. By default the backup is stored on the machine itself, but you can also store it on S3-compatible services like Amazon Web Services (AWS).</p>
+<p>The box makes an incremental backup each night. You can store the backup on any Amazone Web Services S3-compatible service, or other options.</p>
 
 <h3>Configuration</h3>
 
@@ -70,7 +70,7 @@
       <div class="small" style="margin-top: 2px">
         Copy the Public SSH Key above, and paste it within the <tt>~/.ssh/authorized_keys</tt>
         of target user on the backup server specified above. That way you'll enable secure and
-        passwordless authentication from your mail-in-a-box server and your backup server.
+        passwordless authentication from your Mail-in-a-Box server and your backup server.
       </div>
     </div>
     <div id="copy_pub_key_div" class="col-sm">
@@ -98,13 +98,19 @@
   <div class="form-group backup-target-s3">
     <label for="backup-target-s3-host" class="col-sm-2 control-label">S3 Host / Endpoint</label>
     <div class="col-sm-8">
-      <input type="text" placeholder="Endpoint" class="form-control" rows="1" id="backup-target-s3-host">
+      <input type="text" placeholder="https://s3.backuphost.com" class="form-control" rows="1" id="backup-target-s3-host">
     </div>
   </div>
   <div class="form-group backup-target-s3">
-    <label for="backup-target-s3-path" class="col-sm-2 control-label">S3 Path</label>
+    <label for="backup-target-s3-region-name" class="col-sm-2 control-label">S3 Region Name <span style="font-weight: normal">(if required)</span></label>
     <div class="col-sm-8">
-      <input type="text" placeholder="your-bucket-name/backup-directory" class="form-control" rows="1" id="backup-target-s3-path">
+      <input type="text" placeholder="region.name" class="form-control" rows="1" id="backup-target-s3-region-name">
+    </div>
+  </div>
+  <div class="form-group backup-target-s3">
+    <label for="backup-target-s3-path" class="col-sm-2 control-label">S3 Bucket &amp; Path</label>
+    <div class="col-sm-8">
+      <input type="text" placeholder="bucket-name/backup-directory" class="form-control" rows="1" id="backup-target-s3-path">
     </div>
   </div>
   <div class="form-group backup-target-s3">
@@ -272,12 +278,12 @@ function show_custom_backup() {
 	  $("#backup-target-rsync-host").val(spec.host);
 	  $("#backup-target-rsync-path").val(spec.path);
         } else if (r.target.substring(0, 5) == "s3://") {
+          const spec = url_split(r.target);
           $("#backup-target-type").val("s3");
-          var hostpath = r.target.substring(5).split('/');
-          var host = hostpath.shift();
-          $("#backup-target-s3-host-select").val(host);
-          $("#backup-target-s3-host").val(host);
-          $("#backup-target-s3-path").val(hostpath.join('/'));
+          $("#backup-target-s3-host-select").val(spec.host);
+          $("#backup-target-s3-host").val(spec.host);
+          $("#backup-target-s3-region-name").val(spec.user); // stuffing the region name in the username
+          $("#backup-target-s3-path").val(spec.path);
         } else if (r.target.substring(0, 5) == "b2://") {
           $("#backup-target-type").val("b2");
           var targetPath = r.target.substring(5);
@@ -301,7 +307,10 @@ function set_custom_backup() {
   if (target_type == "local" || target_type == "off")
     target = target_type;
   else if (target_type == "s3")
-    target = "s3://" + $("#backup-target-s3-host").val() + "/" + $("#backup-target-s3-path").val();
+    target = "s3://"
+             + ($("#backup-target-s3-region-name").val() ? ($("#backup-target-s3-region-name").val() + "@") : "")
+             + $("#backup-target-s3-host").val()
+             + "/" + $("#backup-target-s3-path").val();
   else if (target_type == "rsync") {
     target = "rsync://" + $("#backup-target-rsync-user").val() + "@" + $("#backup-target-rsync-host").val()
                                                                 + "/" + $("#backup-target-rsync-path").val();